Rachel E. Cherney

The paper compares RNA-protein associations across lncRNAs Airn, Kcnq1ot1, and Xist, identifying HNRNPU's role in long-range Polycomb recruitment by Airn and Kcnq1ot1.

The paper shows a monoclonal antibody against EZH2 cross-reacts with SAFB, highlighting the need for orthogonal assays in studying RNA-chromatin interactions.

The paper shows that Airn lncRNA can deposit Polycomb with potency comparable to Xist when expressed at similar levels, but Xist is more potent when promoter activation is equal.

This study identifies SAFB-associated RNAs in mouse embryonic stem cells and shows SAFB promotes gene expression by binding purine-rich regions in nascent transcripts.

This study identifies the FHA domain of Fkh1 as a factor that enhances ORC binding to a subset of DNA replication origins in budding yeast by interacting with specific DNA sequences.

The paper identifies SPEN-independent transcriptional antiterminator activity in the 5' end of Xist that promotes full-length RNA production and resists silencing.