Elements at the 5' end of Xist harbor SPEN-independent transcriptional antiterminator activity
Jackson B. Trotman, David M. Lee, Rachel E. Cherney, Susan O. Kim, Kaoru Inoue, Megan D. Schertzer, Steve R. Bischoff, Dale O. Cowley, J. Mauro Calabrese
The paper identifies SPEN-independent transcriptional antiterminator activity in the 5' end of Xist that promotes full-length RNA production and resists silencing.
Nucleic Acids Research · Sep 12, 2020Peer-reviewedMolecular Biology