Molecular BiologybioRxivPreprint
Flexibly-oriented double Cdc45-MCM-GINS intermediates during eukaryotic replicative helicase maturation
Lu Liu, Yue Zhang, Jingjing Zhang…·Huiqiang Lou
This study identifies d-CMG intermediates during MCM helicase maturation, showing they are structurally distinct from MCM DHs and functionally immature compared to RPCs.
DOI 10.1101/388470