Author
Beijing Advanced Innovation Center for Food Nutrition and Human HealthORCID 0000-0002-2055-3513Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Yue Jin, Guoqing lan, Jiaxin Zhang…·Wenya Hou
The paper shows that overexpression of WHI7 bypasses the need for Mec1 and Rad53 in Saccharomyces cerevisiae, revealing a transcription-independent role in delaying G1/S transition during replication stress.
Xiaoli Li, Xuejiao Jin, Sushma Sharma…·Huiqiang Lou
The paper identifies Mck1 as a key S-phase checkpoint effector that regulates dNTP homeostasis by modulating RNR and HUG1 expression in response to replication threats.
Haitao Sun, Jiaxin Zhang, Siyu Xin…·Huiqiang Lou
The paper identifies Cul4-Ddb1 ubiquitin ligases as regulators of Esco2-mediated sister chromatid cohesion through Smc3 acetylation in human cells.
Lu Liu, Yue Zhang, Jingjing Zhang…·Huiqiang Lou
This study identifies d-CMG intermediates during MCM helicase maturation, showing they are structurally distinct from MCM DHs and functionally immature compared to RPCs.