Three phylogenetic metrics are compatible with natural evolution of the earliest SARS-CoV-2 sequence
Jean-Noël Lorenzi, François Graner, Thomas Bigot…·Guillaume Achaz
The paper develops a method to detect recombination breakpoints and signs of human-made manipulation in viral sequences, finding no evidence of such manipulation in SARS-CoV-1, MERS-CoV, or SARS-CoV-2.