Xiaodong Liu

NeuroPilot converts heterogeneous intravital neural recordings into stable population activity maps, enabling behavioral decoding and structured neural dynamics analysis across behavioral states.

The paper introduces @fUS, an agentic transcranial fUS imaging platform that enables functional brain imaging in mice with high spatial and temporal resolution, supporting longitudinal studies without surgery.

The paper benchmarks 13 models for predicting single-cell perturbation responses across 25 datasets, finding performance varies with perturbation effect size and evaluation metric.

The paper introduces DeepTrack, a lineage tracing model that combines cellular barcoding with single-cell multi-omics to study cell fate transitions and molecular changes during mammalian development.

PertFormer, a multimodal foundation model, predicts zero-shot functional perturbations and cell fate dynamics, outperforming existing methods and identifying novel tumor treatment targets.

The paper refutes claims that Sendai virus expression undermines the TNT reprogramming method, showing no detectable Sendai virus gene expression in TNT iPS cells.

This study compares six sequencing-based spatial transcriptomic methods using reference tissues, highlighting molecular diffusion as a key variable affecting resolution and identifying unique attributes of spatial transcriptomic data.

This study identifies that amyloid plaque phagocytosis through Hif1α controls microglial phenotypes in Alzheimer’s disease in both mice and humans.

The paper reports the generation of four iPSC lines from PBMCs of an ADHD patient and their healthy sibling, confirming pluripotency and differentiation potential.