Weike Pei

Dissecting human embryonic patterning during organogenesis reveals a rostral midline progenitor population for mesoendoderm induction

The paper identifies a new rostral midline progenitor population in human embryos using spatial transcriptomics and shows their role in mesoendoderm induction.

In vivo multimodal lineage tracing of mammalian development by DeepTrack barcoding

The paper introduces DeepTrack, a lineage tracing model that combines cellular barcoding with single-cell multi-omics to study cell fate transitions and molecular changes during mammalian development.

Steller: a high-resolution platform for spatial clonal tracing of mammalian brain development

Steller improves clonal detection sensitivity in spatial transcriptomics and reveals region-specific spatial clonal architectures in the developing mouse forebrain.

Detection of Somatic Point Mutations Directly from Spatial Transcriptomics Enables in vivo Spatiotemporal Lineage Tracing

SpaceTracer detects somatic SNVs from spatial transcriptomics data to enable lineage tracing in human tissues, revealing tumor progression and immune cell migration.

A spatiotemporal transcriptomic atlas of the mouse placenta reveals glycogen cell-mediated metabolic support essential for fetal viability