Daniel Poppe

The paper refutes claims that Sendai virus expression undermines the TNT reprogramming method, showing no detectable Sendai virus gene expression in TNT iPS cells.

The paper introduces a modular dCas9-based platform for combinatorial epigenome editing, demonstrating its ability to control effector recruitment and spatial organization for improved transcriptional regulation.

The paper examines DNA methylation patterns in neurons derived from mouse ES-cells and cultured primary neurons, finding similarities and differences in mCH deposition compared to in vivo conditions.

This study evaluates deconvolution methods for human brain transcriptome data, finding that cell-type signatures impact accuracy more than methods, and partial methods outperform complete ones.

The paper compares single-cell and single-nucleus RNA-seq workflows in adult mouse kidneys to identify protocol-specific biases in cell type recovery and transcriptional profiles.