Author

Vartika Khanchandani

National University of SingaporeORCID 0000-0002-9331-3051Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Dennis KappeiiD· 2 shared Aghil Soman· 1 shared Akshaya AnbuselvaniD· 1 shared Alexia Hillairet· 1 shared Allison S. Y. ChaniD· 1 shared Anand Devaprasath D. JeyasekharaniD· 1 shared Chai Yeen Goh· 1 shared Charmaine OngiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Dennis KappeiORCID

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2 papers

Recent·Most cited

HOT1 functions as a homodimer to promote ALT-permissive chromatin

Alexia Hillairet, Nurkaiyisah Zaal Anuar, Nivedita Kumar, Vartika Khanchandani, Jia Hui Tee, Michelle Yaochai, Chai Yeen Goh, Falk Butter, Lars Nordenskiöld, Aghil Soman, Dennis Kappei

This study shows HOT1 functions as a homodimer to maintain an ALT-permissive chromatin state at telomeres.

bioRxiv · Nov 3, 2026 · PreprintCell Biology

Genotoxic chemotherapy impedes complement dependent cytotoxicity via Chk1-mediated CD59 regulation

Allison S. Y. Chan, Akshaya Anbuselvan, Patrick William Jaynes, Charmaine Ong, Michał Marek Hoppe, Wai Khang Yong, Vartika Khanchandani, Jie Min Lee, Nurulhuda Binte Mustafa, Irfan Azaman, Phuong Mai Hoang, Guo Hong, Wee Joo Chng, Mark Steven Cragg, Dennis Kappei, , Anand Devaprasath D. Jeyasekharan

This study shows genotoxic chemotherapy increases CD59 expression, reducing complement-dependent cytotoxicity and rituximab efficacy in DLBCL via Chk1-mediated regulation.

bioRxiv · Feb 17, 2025 · PreprintCancer Biology