Author

Tim Fieblinger

Evotec (Germany)ORCID 0000-0002-9348-3595Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:non-human primate· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alaric Falcon· 1 shared Alissa A. CoffeyiD· 1 shared Amy M. PooleriD· 1 shared Andreas FranzeliniD· 1 shared Andreas Karl EngeliD· 1 shared Annemarie Ledeboer· 1 shared Bryan ZeitleriD· 1 shared Chiara MelisiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alaric Falcon

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2 papers

Recent·Most cited

Zinc Finger Repressors mediate widespread PRNP lowering in the nonhuman primate brain and profoundly extend survival in prion disease mice

Shih-Wei Chou, Meredith A Mortberg, Kimberly Marlen, David S. Ojala, Toufan Parman, Michael Howard, Kendrick DeSouza-Lenz, Yuan Lian, Mohadeseh Mehrabian, Matthew R. Tiffany, Annemarie Ledeboer, Patrick Dunn, Jing Hu, Kenia Guzman, Nikita Kamath, , Bryan Zeitler

This study demonstrates that Zinc Finger Repressors (ZFRs) reduce prion protein (PrP) expression in nonhuman primates and extend survival in prion disease mice.

bioRxiv · Mar 5, 2025 · PreprintNeuroscience

cFos ensembles in the dentate gyrus rapidly segregate over time and do not form a stable map of space

Paul J. Lamothe‐Molina, Andreas Franzelin, Lennart Beck, Dong Li, Lea Auksutat, Tim Fieblinger, Laura Laprell, Joachim Ahlbeck, Christine E. Gee, Matthias Kneussel, Andreas Karl Engel, Claus Christian Hilgetag, Fabio Morellini, Thomas G. Oertner

The paper shows that cFos expression in the dentate gyrus changes daily and does not stabilize with spatial memory, yet neurons from early training days still influence later performance.

bioRxiv · Aug 29, 2020 · PreprintNeuroscience