Author

Drena L Dobbs

Iowa State UniversityORCID 0000-0003-4404-9554Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:CRISPR screen· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:zebrafish· 3 Organism:human· 2 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Carla M. ManniD· 3 shared Karl J. ClarkiD· 3 shared Stephen Carl EkkeriD· 3 shared Jeffrey J. EssneriD· 2 shared Jordan M. WelkeriD· 2 shared Maura A. McGrailiD· 2 shared Wesley A. WiersoniD· 2 shared Alec Wehmeier· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetics

Carla M. MannORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Expanding The CRISPR Toolbox With Mad7 In Zebrafish And Human Cells

Wesley A. Wierson, Brandon W. Simone, Zachary WareJoncas, Carla M. Mann, Jordan M. Welker, Bibekananda Kar, Michael J. Emch, Iddo Friedberg, William A.C. Gendron, Michael A. Barry, Karl J. Clark, Drena L Dobbs, Maura A. McGrail, Stephen Carl Ekker, Jeffrey J. Essner

This paper characterizes ErCas12a, a new CRISPR/Cas system, showing it enables efficient DNA repair and gene integration in zebrafish and human cells.

The CRISPR Journal · Dec 1, 2019Peer-reviewedGenetics

GeneWeld: a method for efficient targeted integration directed by short homology

Wesley A. Wierson, Jordan M. Welker, Maira P. Almeida, Carla M. Mann, Dennis A. Webster, Melanie E. Torrie, Trevor J. Weiss, Macy Vollbrecht, Merrina Lan, Kenna C McKeighan, Jacklyn Levey, Zhitao Ming, Alec Wehmeier, Christopher S Mikelson, Jeffrey Haltom, , Jeffrey J. Essner

GeneWeld enables efficient and precise targeted integration in multiple species using CRISPR/Cas9 with minimal homology arms.

bioRxiv · May 25, 2019 · PreprintGenetics

Toward Precision Molecular Surgery: Robust, Selective Induction of Microhomology-mediated End Joining in vivo

Hirotaka Ata, Thomas L. Ekstrom, Gabriel Martínez‐Gálvez, Carla M. Mann, Alexey V. Dvornikov, Kyle J. Schaefbauer, Alvin C. H. Ma, Drena L Dobbs, Karl J. Clark, Stephen Carl Ekker

This paper demonstrates that inducing Microhomology-mediated End Joining (MMEJ) in vivo can generate highly homogeneous mutant alleles, with a novel algorithm provided for predicting MMEJ-inducing sites.

bioRxiv · Apr 16, 2018 · PreprintMolecular Biology