Carla M. Mann

GenSLMs use large language models to analyze SARS-CoV-2 genomes, enabling rapid identification of variants of concern and providing insights into evolutionary dynamics.

This paper characterizes ErCas12a, a new CRISPR/Cas system, showing it enables efficient DNA repair and gene integration in zebrafish and human cells.

GeneWeld enables efficient and precise targeted integration in multiple species using CRISPR/Cas9 with minimal homology arms.

This paper demonstrates that inducing Microhomology-mediated End Joining (MMEJ) in vivo can generate highly homogeneous mutant alleles, with a novel algorithm provided for predicting MMEJ-inducing sites.