Rebecca F. Halperin

Bisbee: A proteomics validated analysis package for detecting differential splicing, identifying splice outliers, and predicting splice event protein effects

Bisbee detects differential splicing and identifies splice outliers with improved sensitivity and specificity using proteomics validated methods.

Tumor cell phenotype and heterogeneity differences in IDH1 mutant vs wild-type gliomas

This study compares tumor cell phenotype and heterogeneity differences between IDH1 mutant and wild-type gliomas using integrated multi-omics data.

Joint analysis of matched tumor samples with varying tumor contents improves somatic variant calling in the absence of a germline sample

LumosVar 2.0 improves somatic variant calling by jointly analyzing tumor and adjacent normal samples without a germline reference.