A long-term organotypic slice culture model of patient high-grade glioma preserving tumor heterogeneity and architecture, and specificity of CAR T cell targeting
Simiao Wang, Ching Ouyang, Heather N. Zook…·Michael E. Barish
Author
Translational Genomics Research InstituteORCID 0000-0002-3382-6787Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
9 papers
Recent·Most cited
Simiao Wang, Ching Ouyang, Heather N. Zook…·Michael E. Barish
Aurosman Sahu, Yue Hao, Angela Baker…·J F Connor
This study shows that iron deficiency in glioblastoma tumors affects immune interactions differently in males and females.
Valerie J. DeLuca, Nathaniel Fox Hansen, Priya Digumarti…·Michael E. Berens
This paper identifies small nucleolar RNAs (snoRNAs) as potential liquid biomarkers for radiation-induced senescence in glioblastoma by analyzing extracellular vesicle cargo changes.
Sharvari Mankame, Hersh Nanda, Maria Kyriakidou…·Floris P Barthel
This study shows that cell-free DNA (cfDNA) can track glioblastoma tumor burden and treatment response over time using in vitro models.
Karan Kumar Budhraja, Bradon R. McDonald, Michelle D. Stephens…·Muhammed Murtaza
Analyzing the positioning and nucleotide sequence at fragment ends in plasma DNA may enable cancer diagnostics.
Michael E. Berens, Anup Sood, Jill S. Barnholtz‐Sloan…·Fiona Ginty
This study compares tumor cell phenotype and heterogeneity differences between IDH1 mutant and wild-type gliomas using integrated multi-omics data.
Sen Peng, Sanhita Rath, Connor Vuong…·Harshil Dhruv
The paper uses single-cell and single-nucleus sequencing to analyze glioblastoma microenvironment composition and interactions, identifying diverse cell types and pathway rewiring.
Rebecca F. Halperin, Winnie S. Liang, Sidharth Kulkarni…·Sara Ann Byron
LumosVar 2.0 improves somatic variant calling by jointly analyzing tumor and adjacent normal samples without a germline reference.
Havell Markus, Tania Contente‐Cuomo, Maria Farooq…·Muhammed Murtaza
The paper evaluates pre-analytical factors affecting plasma DNA analysis by comparing DNA extraction methods and blood collection tubes using a multiplexed ddPCR assay.