Ximena Ibarra-Soria

The paper uses division-resolved single-cell transcriptomics to study T cell activation and identifies gene programmes linked to immune disease by analyzing variant effects on cell division states.

The paper identifies 204 novel genes affecting vertebral development in mice by analyzing whole-gene knockouts from the IMPC dataset and categorizes their phenotypes.

The paper develops a CRISPRi-based single-cell screening approach to map non-coding regulatory elements to genes in primary human CD4+ T cells and demonstrates its utility for GWAS effector gene identification.

This study maps the transcriptional and regulatory changes during mouse somitogenesis, showing accelerated differentiation and lineage-specific programs.

This study identifies asymmetrically expressed genes in the mouse cardiac crescent during left-right symmetry breaking using single-cell RNA sequencing and validates their expression patterns.

The paper investigates how CTCF binding patterns across species contribute to the stability and evolution of TAD boundaries through clustered binding sites.

This study creates a transcriptomic atlas of olfactory mucosae across species to show evolutionary patterns in odor detection capabilities.

The paper uses single cell triple-omics analysis to reveal how epigenetic changes drive germ layer specification in mouse embryos, showing distinct epigenetic priming and remodeling in different lineages.

The paper quantifies olfactory neuron subtype abundance in mice and shows genetic and environmental factors shape olfactory diversity.