Author

Sarah E. Garnish

The University of MelbourneORCID 0000-0002-9415-1517Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

James M. MurphyiD· 2 shared Joanne M. HildebrandiD· 2 shared John SilkeiD· 2 shared Samuel N. YoungiD· 2 shared Adele Preaudet· 1 shared Aleksandra Bankovacki· 1 shared André L. SamsoniD· 1 shared Andrew Ian WebbiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

James M. MurphyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryCell Death and DifferentiationPeer-reviewedFeb 3, 2026

The kinase domain of RIPK3 tunes its scaffolding functions

Shene Chiou, Christopher R. Horne, Komal M. Patel…·James M. Murphy

This study compares three RIPK3 kinase-dead variants to show that their scaffolding functions differ based on kinase domain conformation, not just kinase activity, and highlights implications for inhibitor development.

6 citationstop 1%

mouseexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 1, 2021

Oligomerization-driven MLKL ubiquitylation antagonises necroptosis

Zikou Liu, Laura F. Dagley, Kristy Shield‐Artin…·John Silke

This study demonstrates that MLKL ubiquitylation, triggered by oligomerization, regulates necroptosis by modulating MLKL activity and turnover.

3 citations

mousehuman

𝕏 PostBluesky