This study examines sex differences in structural brain alterations in common epilepsies using neuroimaging data from a large international cohort, finding some regional differences but no significant sex-by-diagnosis interactions.

bioRxiv · Jun 9, 2026 · PreprintNeuroscience

European Autism GEnomics Registry (EAGER): Protocol for a multicentre cohort study and registry

Madeleine Bloomfield, Alexandra Lautarescu, Síofra Heraty, Sarah Douglas, Pierre Violland, Jan Roderik Derk Plas, Anjuli Ghosh, Katrien Van den Bosch, Eliza Eaton, Michael Absoud, Roberta Battini, Ana Blázquez Hinojosa, Nadia Bolshakova, Sven Bölte, Paolo Bonanni, , Tony Charman

EAGER establishes a registry of autistic individuals and those with rare genetic conditions for genomic and phenotypic research, aiming to improve clinical trials and health outcomes through data sharing.

BMJ Open · Jun 1, 2024Peer-reviewedGenetic & Genomic Medicine

A worldwide ENIGMA study on epilepsy-related gray and white matter compromise across the adult lifespan

Judy Chen, Alexander Ngo, Raúl Rodríguez‐Cruces, Jessica Royer, Maria Eugenia Caligiuri, Antonio Gambardella, Luis Concha, Simon Sean Keller, Fernando Cendes, Clarissa Lin Yasuda, Marina K. M. Alvim, Leonardo Bonilha, Ezequiel L. Gleichgerrcht, Niels K. Focke, Barbara A. K. Kreilkamp, , Boris C. Bernhardt

This study examines age-related changes in grey and white matter in TLE patients across the adult lifespan, finding accelerated aging effects after age 55.

bioRxiv · Mar 2, 2024 · PreprintNeuroscience

Excitation/Inhibition balance relates to cognitive function and gene expression in Temporal Lobe Epilepsy: an hdEEG assessment with aperiodic exponent

Gian Marco Duma, Simone Cuozzo, Luc Edward Wilson, Alberto Danieli, Paolo Bonanni, Giovanni Pellegrino

This study uses hdEEG to assess excitation/inhibition balance in TLE patients, finding a correlation with cognitive function and gene expression.

Brain Communications · Jan 1, 2024Peer-reviewedNeuroscience

Altered spread of waves of activities at large scale is influenced by cortical thickness organization in temporal lobe epilepsy: a MRI-hdEEG study

Gian Marco Duma, Giovanni Pellegrino, Giovanni Rabuffo, Alberto Danieli, Lisa Antoniazzi, Valerio Vitale, Raffaella Scotto Opipari, Paolo Bonanni, Pierpaolo Sorrentino

This study investigates how structural brain organization influences altered functional dynamics in temporal lobe epilepsy using MRI and hdEEG data.

bioRxiv · Jul 5, 2023 · PreprintNeuroscience