Author

Wei-Wei Wang

Sir Run Run Shaw HospitalORCID 0000-0002-9461-194XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Chunyou MaoiD· 2 shared Dan-Dan Shen· 2 shared Kun XiiD· 2 shared Yan ZhangiD· 2 shared Hai QiiD· 1 shared Jian-Heng Xue· 1 shared Jiangrong ZhangiD· 1 shared Ping Xu· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMolecular Biology

Chunyou MaoORCID

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2 papers

Recent·Most cited

Dynamic Monomer-Dimer Transition in Ligand-induced Apelin Receptor Activation

Su‐Yu Ji, Wei-Wei Wang, Yixin Yang, Ping Xu, Jiangrong Zhang, Xinyue Zhao, Kun Xi, Shao‐Kun Zang, Dan-Dan Shen, Chunyou Mao, Qingya Shen, Yan Zhang

This study presents cryo-EM structures of the apelin receptor in various oligomeric states to elucidate the dynamic monomer-dimer transition and its role in signaling.

Nature Communications · Apr 3, 2026Peer-reviewedMolecular Biology

Hydration Network Drives Activation and G Protein Selectivity in GPR174

Yingjun Dong, Kun Xi, Zhang Ya-zhi, Jian-Heng Xue, Dan-dan Shen, Shao-Kun Zang, Ruozhu Zhao, Hai Qi, Chunyou Mao, Wei-Wei Wang, Yan Zhang

This study identifies a hydration network in GPR174 that drives receptor activation and G protein selectivity through structural and functional analyses.

bioRxiv · Oct 6, 2025 · PreprintBiophysics