Author
Sir Run Run Shaw HospitalORCID 0000-0001-6602-7116Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Su‐Yu Ji, Wei-Wei Wang, Yixin Yang…·Yan Zhang
This study presents cryo-EM structures of the apelin receptor in various oligomeric states to elucidate the dynamic monomer-dimer transition and its role in signaling.
Xiangyu Ma, Li-Nan Chen, Menghui Liao…·Renjie Chai
This study reveals the constitutive activity and dimerization mechanism of GPR156, explaining its role in auditory function through cryo-EM structures and functional analysis.
Huibing Zhang, Li-Nan Chen, Dehua Yang…·Yan Zhang
The paper reports high-resolution structures of MC4R with agonists and reveals insights into ligand recognition and activation mechanisms.
Wanchao Yin, Chunyou Mao, Xiaodong Luan…·H. Eric Xu
This study reports the structure of SARS-CoV-2 RdRp with and without Remdesivir, showing how the drug inhibits viral RNA replication by terminating chain elongation.
Chunyou Mao, Cangsong Shen, Chuntao Li…·Yan Zhang
The paper presents cryo-EM structures of the GABAB receptor in inactive and active states, revealing structural changes and Gi1 coupling mechanisms.