Author

Sönke Detlefsen

University of Southern DenmarkORCID 0000-0002-9466-2333Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aleksander Ahm KragiD· 1 shared Aleksandra TrifunovićiD· 1 shared Ali AltıntaşiD· 1 shared Andrea Livia Silva RochaiD· 1 shared Andrew Wilson· 1 shared Anita ÖstiD· 1 shared Bjørk Ditlev Marcher LarseniD· 1 shared Caroline A M WeissiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Aleksander Ahm KragORCID

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2 papers

Recent·Most cited

PhysiologyNature CommunicationsPeer-reviewedFeb 24, 2026

Male obesity causes adipose mitochondrial dysfunction in F1 progeny via a let-7-DICER axis.

Chien Hsiang Huang, Joo-Hyun Park, Ali Altıntaş…·Jan‐Wilhelm Kornfeld

This study shows that male obesity affects adipose mitochondrial function in offspring via the let-7-DICER axis, with reversible effects observed in both mice and human semen.

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mousehuman

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Cell BiologyNaturePeer-reviewedApr 16, 2025

The proteomic landscape of proteotoxic stress in a fibrogenic liver disease

Florian A. Rosenberger, Sophia Clara Mädler, Katrine Holtz Thorhauge…·Matthias Mann

This study uses spatial proteomics and machine learning to analyze AATD in human liver tissue, revealing peroxisomal upregulation and a terminal hepatocyte state with distinct proteomic signatures.

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humanproteomics

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