Author

Guilin Tang

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-9482-4806Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Alessandro Pinto· 1 shared Aziz FarhatiD· 1 shared Bonnie WangiD· 1 shared Cheng ZhangiD· 1 shared Christopher R. FlowersiD· 1 shared David Andrew SallmaniD· 1 shared David M. SwobodaiD· 1 shared David Yu ZhangiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

Alessandro Pinto

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2 papers

Recent·Most cited

Scaling Multiplex qPCR Primer Design to 1000-plex using the Degenerate Incomplete Multiplex Primer List Extension (DIMPLE) Algorithm

Alessandro Pinto, Xue Dong, Wei Wu, Sara J. Johnson, Qin Wen, Cheng Zhang, Jana Havey, Bonnie Wang, Guilin Tang, Aziz Farhat, David Yu Zhang, Ghayas C. Issa, Xi Zhang

The paper introduces DIMPLE, a scalable qPCR primer design algorithm that enables 10,000+ primers in a single reaction, achieving low VAF detection and multiplex applications.

bioRxiv · Apr 21, 2026 · PreprintBioengineering

Clonal hematopoiesis is associated with increased toxicity in large B-cell lymphoma patients treated with chimeric antigen receptor T cell therapy

Neeraj Y. Saini, David M. Swoboda, Uri Greenbaum, Jungsheng Ma, Romil D. Patel, Kartik Devashish, Kaberi Das, Mark R. Tanner, Paolo Strati, Ranjit K. Nair, Luis Fayad, Sairah Ahmed, Hun Ju Lee, Swaminathan P. Iyer, Raphael Eric Steiner, , Koichi Takahashi

This study finds that clonal hematopoiesis mutations, particularly in DNMT3A, TET2, and ASXL1, are linked to increased toxicity in patients undergoing anti-CD19 CAR T-cell therapy for large B-cell lymphoma.

bioRxiv · Sep 28, 2021 · PreprintGenetics