Author

Isabelle Couillin

Université d'OrléansORCID 0000-0002-9497-7298Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Nicolas RiteauiD· 2 shared Anne‐Sophie KorganowiD· 1 shared Benoit BriardiD· 1 shared Camille DavidiD· 1 shared Christophe PagetiD· 1 shared Clemente J. BrittoiD· 1 shared Damien Freytag· 1 shared Delphine FouquenetiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Nicolas RiteauORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 22, 2026

Hijacking of inflammasome responses by the complement system during Pseudomonas aeruginosa-Aspergillus fumigatus sur-infection

Sandra Khau, Lucas Treps, Guy Ilango…·Benoit Briard

This study identifies a complement-inflammasome signaling axis that drives excessive inflammation during Pseudomonas aeruginosa and Aspergillus fumigatus co-infection in cystic fibrosis patients.

DOI 10.64898/2026.02.20.707105

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologyEMBO Molecular MedicinePeer-reviewedAug 13, 2025

Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice

Damien Freytag, Stéphane Giorgiutti, Grégoire Hopsomer…·Pauline Soulas-Sprauel

This study identifies T cell exhaustion in STING GOF mice as driven by lymphopenia, independent of type I interferons and intrinsic STING activation.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky