Author

Yi Yang

East China University of Science and TechnologyORCID 0000-0002-9507-7144Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yi Yang9 papers · Johns Hopkins University

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Chen Wu· 1 shared Chengqi LiniD· 1 shared Haitong FangiD· 1 shared Hanyang HuiD· 1 shared Jingjing HeiD· 1 shared Ke Fang· 1 shared Ke WeiiD· 1 shared Kun Gao· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Chen Wu

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2 papers

Recent·Most cited

Treating Myotonic Dystrophy with artificial RNA endonucleases to specifically degrade toxic RNA expansions

Tong Wei, Hanyang Hu, Xin Jiang, Yucheng Li, Wenjian Han, Yi Yang, Xiao Xiao, Miaowei Mao, Zefeng Wang

This paper develops artificial RNA endonucleases (ARCs) that specifically degrade toxic RNA expansions in DM1, showing efficacy in cells and mouse models with low immunogenicity and off-target effects.

bioRxiv · Jun 10, 2025 · PreprintSynthetic Biology

Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics

Peng Xie, Xu Jiang, Jingjing He, Qingyun Pan, Xianfa Yang, Yanying Zheng, Zhuanzhuan Che, Wenli Fan, Chen Wu, Weiheng Zheng, Shuhan Si, Kun Gao, Shiqi Zhu, Ke Fang, Haitong Fang, , Chengqi Lin

The paper uses single-cell multi-omics to study early cardiac lineage specification in mouse embryos, identifying key transcription factors and regulatory networks.

bioRxiv · May 17, 2024 · PreprintMolecular Biology