Author

Mário Hiroyuki Hirata

Universidade de São PauloORCID 0000-0002-9521-7979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Joyce EspositoiD· 2 shared Mayana ZatziD· 2 shared Raul Hernandes BortoliniD· 2 shared Andréia S. SouzaiD· 1 shared Bruna de Gois MacedoiD· 1 shared Caio César Barbosa BomfimiD· 1 shared Camila Ferreira Bannwart CastroiD· 1 shared Camila Ramos SilvaiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

Joyce EspositoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell BiologySkeletal MusclePeer-reviewedMay 2, 2026

iPSC-derived skeletal muscle spheroids for Duchenne Muscular Dystrophy modeling

Joyce Esposito, Felipe de Souza Leite, Igor Neves Barbosa…·Mayana Zatz

This study compares 3D skeletal muscle spheroids (iSMS) with 2D cultures for modeling Duchenne Muscular Dystrophy, finding improved PAX7 expression and altered Notch signaling in iSMS.

DOI 10.1186/s13395-026-00428-3

humanexperimental assay

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ImmunologyMucosal ImmunologyPeer-reviewedMar 14, 2026

CD39 REGULATES P2RX7-MEDIATED LUNG NECROTIC LESIONS IN SEVERE EXPERIMENTAL TUBERCULOSIS

Gislane de Almeida Santos, Igor Santiago-Carvalho, Fabrício Moreira Almeida…·Maria Regina D’Império Lima

This study shows CD39 prevents necrotic lung lesions in tuberculosis by inhibiting P2RX7-mediated macrophage death and inflammation.

3 citationstop 1%

mouseexperimental assay

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GenomicsbioRxivPreprintSep 21, 2023

Muscle cell atrophy induced by miR-155-5p reveals molecular targets in skeletal muscle disorders

Letícia Oliveira Lopes, Sarah Santiloni Cury, Diogo de Moraes…·Paula Paccielli Freire

The paper identifies miR-155-5p-induced gene expression changes in muscle atrophy and links them to disease-related pathways in skeletal muscle disorders.

DOI 10.1101/2023.09.21.558746

humanbulk RNA-seq

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Genetic & Genomic MedicineFrontiers in ImmunologyPeer-reviewedSep 28, 2021

Immunogenetics of resistance to SARS-CoV-2 infection in discordant couples

Erick C. Castelli, Mateus Vidigal de Castro, Michel Satya Naslavsky…·Mayana Zatz

The paper identifies genetic variants associated with resistance to SARS-CoV-2 infection by analyzing discordant Brazilian couples.

56 citationstop 4%

humanwhole-exome sequencing

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