Cell BiologybioRxivPreprint
Neuronal SEL1L-HRD1 ERAD regulates one-carbon metabolism and is essential for motor function and survival
Mauricio Torres, You Lu, Brent Pederson…·Ling Qi
This study shows that neuronal SEL1L-HRD1 ERAD is critical for one-carbon metabolism, motor function, and survival, with loss leading to severe neurological defects.