Author

Solomon H. Snyder

Johns Hopkins UniversityORCID 0000-0002-6818-7022Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adele M. Snowman· 3 shared Bindu Diana PauliD· 3 shared Chirag VasavdaiD· 3 shared Cristina RiccoiD· 2 shared Eugenio BaroneiD· 2 shared Evan R. SemenzaiD· 2 shared Michael D. KornbergiD· 2 shared Robin RoychaudhuriiD· 2 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersNeuroscience

Adele M. Snowman

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Author profile →

5 papers

Recent·Most cited

Biliverdin Reductase A is a major determinant of neuroprotective Nrf2 signaling

Chirag Vasavda, Ruchita Kothari, Navneet Ammal Kaidery, Suwarna Chakraborty, Sunil Jamuna Tripathi, Ryan S. Dhindsa, Samaneh Saberi, Julia E. Lefler, Priyanka Kothari, Kalyani Chaubey, Cristina Ricco, Adele M. Snowman, Michael C. Ostrowski, Eugenio Barone, Lakshminarayan M. Iyer, , Bindu Diana Paul

This paper identifies a novel non-enzymatic role for BVRA in modulating Nrf2 signaling, revealing its importance in neuroprotection and potential as a therapeutic target for neurodegenerative diseases.

bioRxiv · Jun 4, 2025 · PreprintNeuroscience

Serine Racemase mediates Subventricular Zone Neurogenesis via Fatty acid Metabolism.

Robin Roychaudhuri, Hasti Atashi, Solomon H. Snyder

This study shows that serine racemase (SR) influences adult subventricular zone (SVZ) neurogenesis by regulating fatty acid synthesis and lipid metabolism.

Stem Cell Reports · Jun 22, 2023Peer-reviewedNeuroscience

Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

Chirag Vasavda, Evan R. Semenza, Jason Liew, Ruchita Kothari, Ryan S. Dhindsa, Shruthi Shanmukha, Anthony L. Lin, Robert A. Tokhunts, Cristina Ricco, Adele M. Snowman, Lauren K. Albacarys, Francesco Pastore, Cristian Ripoli, Claudio Grassi, Eugenio Barone, , Solomon H. Snyder

This study identifies biliverdin reductase (BVR) as a bridge between FAK/Pyk2 and Src, showing its role in synaptic signaling and learning/memory deficits in BVR-null mice.

Science Signaling · May 10, 2022Peer-reviewedNeuroscience

D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain

Evan R. Semenza, Maged M. Harraz, Efrat Abramson, Adarsha P. Malla, Chirag Vasavda, Moataz M. Gadalla, Michael D. Kornberg, Solomon H. Snyder, Robin Roychaudhuri

This study identifies D-cysteine as an endogenous regulator of neural progenitor cell dynamics in the mammalian brain, showing its antiproliferative effects and role in cortical development.

Proceedings of the National Academy of Sciences · Sep 23, 2021Peer-reviewedNeuroscience

The glutathione cycle shapes synaptic glutamate activity

Thomas W. Sedlak, Bindu Diana Paul, Gregory Parker, Lynda D. Hester, Adele M. Snowman, Yu Taniguchi, Atsushi Kamiya, Solomon H. Snyder, Akira Sawa

The paper investigates the role of the glutathione cycle in regulating synaptic glutamate levels and excitatory neurotransmission, finding that glutathione acts as a reservoir for glutamate.

Proceedings of the National Academy of Sciences · Jan 28, 2019Peer-reviewedNeuroscience