Michael John Moore

The paper develops a human microphysiological model of dorsal root ganglion-spinal cord dorsal horn circuitry that mimics opioid-induced effects through electrophysiological responses.

This study demonstrates LTP and closed-loop learning in paired brain organoids, showing BDNF's role in enhancing plasticity and linking game performance to cognitive function for CNS drug discovery.

This paper introduces a 3D peripheral nerve-on-a-chip model to predict neurotoxicity, showing it captures dose- and time-dependent nerve damage similar to human clinical exposures.