Martina Crispo

IFNγ at the crossroads of systemic protection and brain vulnerability to coronavirus infection

This study investigates the dual role of IFNγ in coronavirus infection, showing it limits systemic viral spread but increases brain vulnerability, suggesting potential therapeutic modulation.

Systemic dissemination, reproductive tissue tropism and gestational stage-dependent placental responses during Mayaro virus infection in a murine model

This study uses a murine model to track Mayaro virus dissemination and tissue tropism, showing gestational stage affects fetal infection and suggests non-vector transmission routes.

Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling

This study shows that deleting Dbc1 in adipocytes does not cause healthy obesity but reveals a role for Dbc1 in inflammation during obesity.

Generation and characterization of Ccdc28b mutant mice links the Bardet-Biedl associated gene with social behavioral phenotypes

This paper generates Ccdc28b mutant mice and finds they exhibit social behavioral defects and autism-like features, suggesting a link between CCDC28B and autism spectrum disorder beyond its role as a modifier of Bardet-Biedl syndrome.