Elisa Kreibich

The paper measures RNA Polymerase II occupancy at promoters in mouse and Drosophila, finding lower occupancy and higher turnover in mammals.

The paper uses single molecule multi-omics to show DNA methylation can block transcription factor binding at cell-type-specific enhancers, but not all enhancers.

IMPLICON is a high-throughput method for measuring DNA methylation at imprinted regions with high coverage and resolution, validated in mice and adapted for human use to detect imprinting errors.

This study identifies Dppa2 and Dppa4 as upstream regulators of the Dux-driven zygotic transcriptional programme in 2C-like cells.