Author
QB3ORCID 0000-0002-9625-0121Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Sydney V. Oraskovich, Kazuomori K. Lewis, Joost van Haasteren…·David V. Schaffer
ELiPS generates and screens short, strong promoters for gene therapy, outperforming existing promoters in vitro and enabling therapeutic expression in vivo.
Hunter J. Johnson, David M. McMullin, Joshua A. Zimmermann…·David V. Schaffer
The paper uses optogenetic WNT activation in human gastruloids to study germ layer self-organization and finds it drives mesendoderm differentiation and patterning.
Sarah J. Yang, Jackson Travis Del Bonis-O’Donnell, Francesca Giordani…·Markita Patricia Landry
The paper uses near-infrared catecholamine nanosensors to image dopamine release in Huntington's Disease model mice, finding decreased dopamine hotspot number, intensity, and fidelity in late-stage disease.
Leah C. Byrne, Timothy P. Day, Meike Visel…·John G. Flannery
This study uses directed evolution to create AAV vectors with enhanced gene delivery to the outer retina in primates.