ImmunologybioRxivPreprint
Targeting Regnase-1 unleashes CAR T cell antitumor activity for osteosarcoma and creates a proinflammatory tumor microenvironment
Adeleye Oluwatosin Adeshakin, Hao Shi, S. Scott Perry…·Stephen M Gottschalk
This study shows that deleting Regnase-1 in CAR T cells enhances their antitumor activity against osteosarcoma by creating a proinflammatory tumor microenvironment.
2 citations