Author

Christopher C. DeRenzo

St. Jude Children's Research HospitalORCID 0000-0001-6127-4601Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Adeleye Oluwatosin AdeshakiniD· 1 shared Bella Raykowski· 1 shared Ben Yi TewiD· 1 shared Chi Woo YooniD· 1 shared Deanna M. LangfittiD· 1 shared Giedre KrenciuteiD· 1 shared Hao ShiiD· 1 shared Heather SheppardiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Adeleye Oluwatosin AdeshakinORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 20, 2026

Transcription Factor-Mediated Reprogramming of Cancer-Associated Fibroblasts Reveals Targetable Vulnerabilities in Solid Tumors

Nan Sook Lee, Priyankan Datta, Yixuan Huang…·Ishwar K. Puri

This study reprograms cancer-associated fibroblasts using transcription factors to reduce therapy resistance and enhance CAR T cell efficacy in solid tumors.

DOI 10.64898/2026.04.15.718753

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 20, 2025

Targeting Regnase-1 unleashes CAR T cell antitumor activity for osteosarcoma and creates a proinflammatory tumor microenvironment

Adeleye Oluwatosin Adeshakin, Hao Shi, S. Scott Perry…·Stephen M Gottschalk

This study shows that deleting Regnase-1 in CAR T cells enhances their antitumor activity against osteosarcoma by creating a proinflammatory tumor microenvironment.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky