Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication.
Paula Armina V. Buco, Wilson Castillo‐Tandazo, Alistair Morgan Chalk…·Carl R. Walkley
This study identifies KLHDC3 as a rescue factor for RECQL4 mutations, showing that low levels of a truncated RECQL4 protein can support DNA replication without requiring its ATPase or helicase domains.