Author
St Vincents Institute of Medical ResearchORCID 0000-0003-3394-1811Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Jacki E. Heraud-Farlow, Scott Taylor, Ankita Goradia…·Carl R. Walkley
This study shows ADAR1p150 suppresses immunogenicity from tonic type I IFN-induced transcripts through editing-dependent and -independent mechanisms.
Effrosyni Antonopoulou, Chun Li, Amen Shamin…·Isabel M. Pires
This study shows WSB-1 regulates DNA repair and enhances sensitivity to DNA damage response inhibitors in breast cancer.
Emily S. Pyne, Mark Reardon, Martin Christensen…·Isabel M. Pires
This study uses a spheroid-on-chip system to analyze how interstitial fluid flow and hypoxia affect cancer gene expression and identifies potential biomarkers.
Shi-Bin Hu, Jacki E. Heraud-Farlow, Tao Sun…·Jin Billy Li
The paper shows that ADAR1p150 prevents MDA5 and PKR activation through distinct mechanisms, preventing fatal autoinflammation.
Zhen Liang, Scott Taylor, Ankita Goradia…·Carl R. Walkley
The paper reports that the common ADAR1p150 mutation P193A is well tolerated in mice, with reduced severity when combined with MDA5 loss.