Maria Eleni Kastriti

A uniform tissue-clearing framework and mesoSPIM-ultra enable cm-scale single-neuron tracing

The paper introduces a tissue-clearing framework and mesoSPIM-ultra system for large-scale single-neuron tracing in cleared mouse tissue.

SOX2+ sustentacular cells are stem cells of the postnatal adrenal medulla

This study identifies SOX2+ sustentacular cells as stem cells for postnatal adrenal medulla chromaffin cells, showing their ability to generate both adrenaline and noradrenaline lineages and maintain homeostasis via WNT6 secretion.

The main duct of von Ebner's glands is a source of Sox10+ taste bud progenitors and susceptible to pathogen infections

Motor nerves direct the development of the sympathetic nervous system

This study shows that motor nerves guide the development of sympathetic ganglia by directing the migration and differentiation of neural crest-derived sympathoblasts.

Molecular and spatial design of early skin development

This study uses single-cell transcriptomics and spatial analysis to map early mouse skin development, revealing new cell types and interactions.

Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics

The paper identifies microheterogeneity in embryonic chromaffin cells and their differentiation paths using single-cell transcriptomics in mice.

RNA velocity in single cells

Unspliced versus spliced mRNA in standard scRNA-seq gives RNA velocity, a per-cell vector predicting future state over hours, validated in neural crest and used to trace mouse hippocampal lineages.