John J. Dennehy

Selective Packaging of Rotavirus Double-Layered Particles into Host Microvesicles

This study shows rotavirus uses host microvesicles to transmit immature double-layered particles, enabling non-lytic spread and bypassing outer-capsid-dependent entry.

Genomic Characterization and Therapeutic Potential of the Lytic Bacteriophage Curly against Klebsiella pneumoniae in Human Innate Immune Cells and a Murine Pneumonia Model

This study characterizes a bacteriophage, Curly, against Klebsiella pneumoniae, showing its efficacy in reducing bacterial burden and inflammation in human cells and a mouse model.

A Chemostat-Based Model for Growing Bacterial Biofilms

This paper introduces a chemostat-based experimental platform to study bacterial biofilms and their interactions with environments, showing biofilms grow larger and produce migrants in chemostats.

Translation Efficiency Impacts Phage Lysis Timing and Its Precision in Single Cells

This study shows that modulating holin translation efficiency affects phage lysis timing and precision in E. coli, revealing how phages optimize replication and transmission.

The role of incoherent feedforward circuits in regulating precision of event timing

The paper investigates how an incoherent feedforward circuit involving holin and antiholin proteins regulates the precision of lysis timing in bacteriophage lambda.