Sean‐Paul Nuccio

Targeting catecholate siderophore systems enables precision depletion of gut enterobacteria during colitis

This study shows that targeting catecholate siderophore systems reduces AIEC colonization in colitis by immunization, preserving gut microbiome composition.

Commensal Escherichia coli colonization triggers Peyer's patch development

This study identifies Escherichia coli as a key driver of B cell accumulation in Peyer's patches via CXCR2-dependent mechanisms involving curli amyloid fibers and TLR2 signaling.

PgtE protease enables virulent Salmonella to evade C3-mediated serum and neutrophil killing

This study shows that PgtE protease in virulent Salmonella Typhimurium helps evade complement-mediated killing by cleaving C3, enabling systemic spread.