Author

Fabrice Laurent

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementORCID 0000-0002-9687-7952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Sonia Lacroix‐LamandéiD· 2 shared Adeline Goubil· 1 shared Alexandre BougdouriD· 1 shared Alix Sausset· 1 shared Andréa RauiD· 1 shared Axel Gouin· 1 shared Carine Mazal· 1 shared Cédric CabauiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

Sonia Lacroix‐LamandéORCID

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3 papers

Recent·Most cited

Mechanistic insights into the activity of Benzoxaboroles against Cryptosporidium parvum: CPSF3 targeting and resistance implications

Janine Wenker, Laurence Braun, Christopher Swale, Axel Gouin, Julien Pichon, Laura Sedano, Thomas Baty, Irina Dobrescu, Marco Lalle, Mohamed‐Ali Hakimi, Alexandre Bougdour, Fabrice Laurent

This study investigates how benzoxaboroles inhibit CPSF3 in Cryptosporidium parvum, identifies resistance mechanisms, and shows that AN7973 can overcome resistance.

bioRxiv · Oct 9, 2025 · PreprintMicrobiology

Exploring the impact of digestive physicochemical parameters of adults and infants on the pathophysiology of Cryptosporidium parvum using the dynamic TIM-1 gastrointestinal model

Julie Tottey, Lucie Etienne‐Mesmin, Sandrine Chalançon, Alix Sausset, Sylvain Denis, Carine Mazal, Christelle Blavignac, Guillaume Sallé, Fabrice Laurent, Stéphanie Blanquet‐Diot, Sonia Lacroix‐Lamandé

This study investigates how age-related digestive parameters affect Cryptosporidium parvum infection using an in vitro gastrointestinal model, finding differences in sporozoite release, activity, and invasiveness between adults and infants.

Gut Pathogens · Oct 1, 2024Peer-reviewedMicrobiology

Transcriptome and chromatin structure annotation of liver, CD4+ and CD8+ T cells from four livestock species.

Sylvain Foissac, Sarah Djebali, Kylie Munyard, Nathalie Vialaneix, Andréa Rau, Kévin Muret, Diane Esquerré, Matthias Zytnicki, Thomas Derrien, Philippe Bardou, Fany Blanc, Cédric Cabau, Elisa Crisci, Sophie Dhorne‐Pollet, Françoise Drouet, , Elisabetta Giuffra

The paper annotates transcriptomes and chromatin structures in liver and T cells from four livestock species using RNA-seq, ATAC-seq, and Hi-C, revealing conserved regulatory elements and genome organization patterns.

bioRxiv · May 16, 2019 · PreprintGenomics