Christopher Swale

Genome-wide chromatin reset at the onset of leg regeneration in pancrustaceans

The paper investigates chromatin state reorganization during leg regeneration in pancrustaceans, finding a conserved sequence of chromatin resetting and pioneer factor activation across species.

Pentachloropseudilin disrupts multiple steps of the Toxoplasma gondii lytic cycle, consistent with predicted multi-myosin engagement

This paper shows pentachloropseudilin disrupts multiple stages of the Toxoplasma gondii lytic cycle by interfering with different myosins, suggesting it as a tool for studying myosin functions and a potential antiparasitic strategy.

Mechanistic insights into the activity of Benzoxaboroles against Cryptosporidium parvum: CPSF3 targeting and resistance implications

This study investigates how benzoxaboroles inhibit CPSF3 in Cryptosporidium parvum, identifies resistance mechanisms, and shows that AN7973 can overcome resistance.

Hydra domain drives SNF2L multimerization and marks ISWI diversification in parasites

The paper identifies Hydra, a novel domain in TgSNF2L that drives multimerization and contributes to ISWI diversification in Toxoplasma gondii.