Author

Якубовская Марианна Геннадиевна

Ministry of Health of the Russian FederationORCID 0000-0002-9710-8178Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Кирсанов Кирилл ИгоревичiD· 2 shared Alfiya F. SafinaiD· 1 shared Andrei V. GudkoviD· 1 shared Britney Lipchick· 1 shared Catherine A. BurkhartiD· 1 shared Costakis G. FrangouiD· 1 shared Ekaterina A. LesovayaiD· 1 shared Elimelech NesheriD· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Кирсанов Кирилл ИгоревичORCID

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2 papers

Recent·Most cited

Artificial introns for effective expression of transgenes in mammalian cells

Д. С. Набережнов, Ekaterina A. Lesovaya, Кирсанов Кирилл Игоревич, Якубовская Марианна Геннадиевна

The paper generates and tests short artificial introns to enhance transgene expression in mammalian cells, identifying 12 effective variants.

bioRxiv · Sep 1, 2021 · PreprintMolecular Biology

Transcription of Repeats Activates INterferon (TRAIN) in response to chromatin destabilization induced with anti-cancer small molecule

Katerina I. Leonova, Alfiya F. Safina, Elimelech Nesher, Poorva Sandlesh, Rachel N. Pratt, Catherine A. Burkhart, Britney Lipchick, Costakis G. Frangou, Igor E. Koman, Jianmin Wang, Кирсанов Кирилл Игоревич, Якубовская Марианна Геннадиевна, Andrei V. Gudkov, Katerina V. Gurova

The paper shows that chromatin destabilizing drugs like curaxin induce an interferon response (TRAIN) through repeat transcription, independent of p53 status, and may prevent cancer by eliminating epigenetically unstable cells.

bioRxiv · Jun 28, 2017 · PreprintMolecular Biology