Author

Saulius Ročka

Vilnius UniversityORCID 0000-0002-9715-641XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexei VerkhratskyiD· 2 shared Gediminas LukšysiD· 2 shared Ugnė KuliešiūtėiD· 2 shared Urtė NeniškytėiD· 2 shared Agnė PociūtėiD· 1 shared Aida KaušylėiD· 1 shared Akvilė Rudėnaitė· 1 shared Augustas PivoriūnasiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersNeuroscience

Alexei VerkhratskyORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Varicose-projection astrocytes: a reactive phenotype associated with neuropathology

Caterina Ciani, Giulio Pistorio, Simona Giancola, Marika Mearelli, Francesca Emma Mongelli, Delaram Forouzeh, Luca Mio, Paula Ramos‐Gonzalez, Carlos Matute, Ugnė Kuliešiūtė, Sari Elena Dötterer, Gediminas Lukšys, Saulius Ročka, Urtė Neniškytė, Marya Ayub, , Carmen Falcone

This study identifies varicose projection astrocytes as a reactive phenotype associated with neuropathology, showing their presence in humans, mice, and tigers and their induction by inflammation.

bioRxiv · Mar 17, 2025 · PreprintNeuroscience

Integrity assay for messenger RNA in mouse and human brain samples and synaptosomal preparations

Daina Bujanauskienė, Kajus Merkevičius, Ugnė Kuliešiūtė, Jaroslav Denkovskij, Simonas Kutanovas, Gediminas Lukšys, Saulius Ročka, Eiva Bernotienė, Urtė Neniškytė

The paper introduces a RT-qPCR assay to assess mRNA integrity in brain and subcellular samples, showing it outperforms RIN in correlation with housekeeping gene expression.

iScience · Jun 29, 2024Peer-reviewedMolecular Biology

Plasma of COVID-19 patients does not alter electrical resistance of human endothelial blood-brain barrier in vitro.

Agnė Pociūtė, Karolina Kriaučiūnaitė, Aida Kaušylė, Birutė Zablockienė, Tadas Alčauskas, Augustė Jelinskaitė, Akvilė Rudėnaitė, Ligita Jančorienė, Saulius Ročka, Alexei Verkhratsky, Augustas Pivoriūnas

This study investigates whether COVID-19 patient plasma affects BBB integrity in vitro using iBECs and finds no direct effect on TEER, but identifies elevated inflammatory factors in plasma.

bioRxiv · Sep 28, 2023 · PreprintNeuroscience