Varicose-projection astrocytes: a reactive phenotype associated with neuropathology
Caterina Ciani, Giulio Pistorio, Simona Giancola, Marika Mearelli, Francesca Emma Mongelli, Delaram Forouzeh, Luca Mio, Paula Ramos‐Gonzalez, Carlos Matute, Ugnė Kuliešiūtė, Sari Elena Dötterer, Gediminas Lukšys, Saulius Ročka, Urtė Neniškytė, Marya Ayub, , Carmen Falcone
This study identifies varicose projection astrocytes as a reactive phenotype associated with neuropathology, showing their presence in humans, mice, and tigers and their induction by inflammation.
bioRxiv · Mar 17, 2025 · PreprintNeuroscience