Proteomic characterization of sporadic clear cell renal cell carcinoma reveals a matrix-dense pseudocapsule and heterogeneous tumor subtypes
Tobias Feilen, Grigor Andreev, Manuel Rogg, Miguel Cosenza‐Contreras, Niko Pinter, Max Zirngibl, Antonia Elsässer, Pitter F. Huesgen, Markus Tobias Grabbert, Christoph Schell, Oliver Schilling
This study uses proteomics to characterize sporadic ccRCC, identifying a matrix-dense pseudocapsule and five tumor subtypes with distinct biological features.
bioRxiv · Oct 23, 2025 · PreprintMolecular Biology