Author

Paul Michael Maciocia

University College LondonORCID 0000-0002-9757-8073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Jongwon YooniD· 2 shared Amalie GrenoviD· 1 shared Ana Rodríguez-RoncheliD· 1 shared Andria A. Lytridou· 1 shared Anisur RahmaniD· 1 shared Anna MikolajczakiD· 1 shared Bahar Artım-EseniD· 1 shared Carola G. VinuesaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Jongwon YoonORCID

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2 papers

Recent·Most cited

Endothelin receptor blockade potentiates adoptive T cell and CAR T cell therapies

Charys Papagregoriou, Fotios Mpekris, Jongwon Yoon, Georgios Kastrappis, Andria A. Lytridou, Maria Thrasyvoulou, Konstantinos Symeonidis, Christina Pitsillidou, Constantina Neophytou, Myrofora Panagi, Chrysovalantis Voutouri, Maria Iakovou, Gregoria Gregoriou, Triantafyllos Stylianopoulos, Paul Michael Maciocia, , Philippos Demetriou

This study shows that blocking the endothelin receptor pathway enhances T cell and CAR T cell therapies in cancer models by improving antitumour responses and durable immunity.

bioRxiv · Sep 6, 2026 · PreprintImmunology

Autoantibody origins in lupus and in relapse post CAR-T therapy

Amalie Grenov, Jongwon Yoon, Daniel M. Snell, Anna Mikolajczak, Hao Wang, Erdem Gürel, Ana Rodríguez-Ronchel, Gülçin Yeğen, Lydia S.H. Lee, Bahar Artım-Esen, Anisur Rahman, Paul Michael Maciocia, Carola G. Vinuesa

The paper shows that autoantibody production in lupus is sustained by continuous B cell differentiation, not long-lived plasma cells, and relapse after CAR-T therapy occurs via new B cells.

bioRxiv · Oct 20, 2025 · PreprintImmunology