Author

Konstantinos Symeonidis

University Hospital Bonn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Andria A. Lytridou· 1 shared Ann-Kathrin WeieriD· 1 shared Apurba SarkariD· 1 shared Charys Papagregoriou· 1 shared Christina PitsillidouiD· 1 shared Chrysovalantis VoutouriiD· 1 shared Constantina Neophytou· 1 shared Dirk BaumjohanniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Andria A. Lytridou

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Author profile →

2 papers

Recent·Most cited

Endothelin receptor blockade potentiates adoptive T cell and CAR T cell therapies

Charys Papagregoriou, Fotios Mpekris, Jongwon Yoon, Georgios Kastrappis, Andria A. Lytridou, Maria Thrasyvoulou, Konstantinos Symeonidis, Christina Pitsillidou, Constantina Neophytou, Myrofora Panagi, Chrysovalantis Voutouri, Maria Iakovou, Gregoria Gregoriou, Triantafyllos Stylianopoulos, Paul Michael Maciocia, , Philippos Demetriou

This study shows that blocking the endothelin receptor pathway enhances T cell and CAR T cell therapies in cancer models by improving antitumour responses and durable immunity.

bioRxiv · Sep 6, 2026 · PreprintImmunology

Multiple clustered centrosomes in antigen-presenting cells foster T cell activation without MTOC polarization

Isabel Stötzel, Ann-Kathrin Weier, Apurba Sarkar, Subhendu Som, Luisa Bach, Peter Konopka, Eliška Miková, Shaunak Ghosh, Jan Böthling, Mirka Homrich, Laura Schaedel, Uli Kazmaier, Konstantinos Symeonidis, Stefan Ebner, Philip Weidner, , Eva Kiermaier

This study shows that multiple clustered centrosomes in antigen-presenting cells enhance T cell activation by positioning near the cell center, unlike T cells where centrosomes polarize toward the immune synapse.

Nature Communications · Jan 13, 2026Peer-reviewedCell Biology