Author

April A. N. Rose

Jewish General HospitalORCID 0000-0002-9845-4603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alejandro Schcolnik‐CabreraiD· 1 shared Anavasadat Sadr Hashemi NejadiD· 1 shared Caroline CapdevielleiD· 1 shared Donia Issa· 1 shared Frédérick A. MalletteiD· 1 shared Ivan TopisirovićiD· 1 shared Laura HuleaiD· 1 shared Martín RofféiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alejandro Schcolnik‐CabreraORCID

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1 paper

Recent·Most cited

eIF4A inhibition disrupts resistance-associated translational and metabolic programs in BRAF-mutant melanoma

Alejandro Schcolnik‐Cabrera, Meriem Takdenti, Anavasadat Sadr Hashemi Nejad, Zaynab Nouhi, Sarah St-Amand, Caroline Capdevielle, Donia Issa, Mélody Riaud, April A. N. Rose, Mireille Khacho, Frédérick A. Mallette, Martín Roffé, Tommy Alain, Ivan Topisirović, Laura Hulea

This study shows eIF4A inhibition disrupts resistance mechanisms in BRAF-mutant melanoma by targeting translational and metabolic programs, improving tumor control when combined with BRAF inhibitors.

bioRxiv · Sep 8, 2026 · PreprintCancer Biology