Mustafa Kezar Khokha

Equine Parentage Testing with SNPs and beyond: developing a platform independent panel

The paper develops a platform-independent SNP panel for equine parentage testing, demonstrating its robustness and utility for breed identification and disease assays.

A yeast model reveals the SMAD3 nuclear import mechanism

The paper uses a yeast model to identify the nuclear import mechanism of SMAD3, showing that the MH1 domain functions as an importin binding surface.

Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs

The paper presents high-quality genomes and chromatin structure analyses of frogs, revealing conserved ancestral chromosomes and stable genome evolution.

Expanding EMC Foldopathies: Topogenesis Deficits Alter the Neural Crest

The paper investigates the role of EMC9 and EMC10 in neural crest development using Xenopus models, finding similar phenotypes to EMC1 loss of function in craniofacial development.

Kap-β2/Transportin mediates β-catenin nuclear transport in Wnt signaling

This study identifies Kap-β2/Transportin as the nuclear transport receptor for β-catenin in Wnt signaling, showing its role in nuclear import and potential as a therapeutic target.

Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome

The paper identifies novel truncating mutations in CTNND1 associated with craniofacial and cardiac anomalies, expanding the known phenotypic spectrum of the gene.

WDR5 stabilizes actin architecture to promote multiciliated cell formation

The paper identifies WDR5's role in stabilizing apical actin architecture to support multiciliated cell formation and function.

CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing

This study shows that LbCpf1 enables efficient homology-directed repair and temperature-controlled genome editing in zebrafish, improving targeted DNA integration.