Remco Loos

This paper improves the assessment of deep learning models for drug-target interaction prediction by addressing dataset biases and proposing a more accurate evaluation framework.

This study shows that maternal genotype influences global DNA methylation patterns in mice, with prenatal maternal effects driving differences between inbred strains.

This study compares RNA-seq and junction arrays for detecting splice events using a cross-platform algorithm, finding RNA-seq superior for novel events but both coherent for known regions.

This study compares the epigenomes of neutrophils and monocytes to identify regulatory elements and chromatin states, revealing differences in enhancer activity and DNA methylation.

This study shows the NuRD complex regulates enhancer chromatin structure and Mediator access to control transcription during lineage commitment in ES cells.