Pan-cancer N-glycoproteomic atlas of patient derived xenografts uncovers FAT2 as a therapeutic target for head and neck cancers
Meinusha Govindarajan, Salvador Mejia‐Guerrero, Shawn C. Chafe, Shahbaz Khan, Wei Shi, Matthew Waas, Martín A. Rossotti, Amanda Khoo, Lydia Liu, Vladimir Ignatchenko, Simona Principe, Lusia Sepiashvili, Greg Hussack, Nazanin Tatari, Chitra Venugopal, , Thomas Kislinger
This paper uses N-glycoproteomics to analyze patient-derived xenografts, identifies FAT2 as a therapeutic target for head and neck cancers, and validates its role in tumor growth and CAR T cell activity.
Cell Reports Medicine · Jan 23, 2026Peer-reviewedCancer Biology