Author

Sutapa Chakrabarti

Freie Universität BerlinORCID 0000-0002-9877-173XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Guangpu XueiD· 2 shared Alexandrina Machado de AmorimiD· 1 shared Andrea Brigitte Eberle· 1 shared Cecilia Perez-BorrajeroiD· 1 shared Clemens KrageiD· 1 shared Henning UrlaubiD· 1 shared Janosch HennigiD· 1 shared Juliane BethmanniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiochemistry

Guangpu XueORCID

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3 papers

Recent·Most cited

Molecular BiologyRNAPeer-reviewedOct 7, 2025

UPF1 shuttles between nucleus and cytoplasm independently of its RNA binding and ATPase activities

Sofía Nasif, Andrea Brigitte Eberle, Karin Schranz…·Oliver Mühlemann

This study shows UPF1 shuttles between nucleus and cytoplasm without needing its RNA binding or ATPase activities, with RNA binding causing cytoplasmic retention.

1 citation

humanexperimental assay

BiochemistrybioRxivPreprintFeb 23, 2025

Molecular mechanisms of recruitment, function and regulation of UPF1 in histone mRNA decay

Alexandrina Machado de Amorim, Guangpu Xue, Theresa Dittmers…·Sutapa Chakrabarti

This study identifies the molecular interactions of UPF1 in histone mRNA decay, showing how SLBP and UPF2 regulate its unwinding activity and degradation efficiency.

1 citation

experimental assaychromatin & epigenetic regulation

BiochemistryNucleic Acids ResearchPeer-reviewedSep 14, 2024

Functional implications of the interaction of the SARS-CoV-2 Nucleocapsid protein with factors involved in nonsense-mediated mRNA decay

Megha Mallick, Volker Boehm, Guangpu Xue…·Sutapa Chakrabarti

This study identifies interactions between SARS-CoV-2 N-protein and NMD factors, showing N inhibits UPF1 activity and may stabilize viral RNA.

7 citations

humanproteomics